Home » SiR-A novel vector for CRISPR delivery into the CNS

SiR-A novel vector for CRISPR delivery into the CNS

Modality

Advanced therapies

Therapeutic area

Neuroscience

Advantages

The vector allows for a highly site specific level of infection at a very low concentration. Moreover, retrograde movement of Rabies virus means the vector could be delivered at the spinal cord or peripheral motor neurones, before tracing to a specific cell type deeper in the CNS.

Background info

A neurotropic, attenuated Rabies virus vector that can be used to deliver a payload to the CNS before self-inactivating, thereby allowing for gene editing.

Indication

Central nervous system disorders

Intellectual property

Granted patents and pending patent applications that entered their respective national stage from WO2018203049

Contact us

Name(Required)
Email(Required)
Please let us know what's on your mind. Have a question for us? Ask away.

In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. If you would like your data to be removed, please email info@lifearc.org.

Please see our Privacy Policy in relation to the personal data you submit to us through this page.