Translational Challenge
Motor Neuron Disease
Our vision is a world where motor neuron disease (MND) is preventable and treatable.
Motor neuron disease (MND) affects the nerves in the brain and spinal cord that help tell muscles what to do.
We still know far too little about how to predict the onset or progression of MND, or to develop treatments or cures.
We want to use our expertise in early-stage science to progress discoveries that can intervene early, provide better treatments and improve the quality of life for those living with MND.
What do we want to achieve?
- Contribute to making medicines and diagnostics
- Detect and diagnose MND earlier
- Connect experts across MND research
- Unblock barriers that keep scientific discoveries from reaching patients
- Listen and learn from people living with MND
How you can work with us
We partner and invest in the work of academics, charities, healthcare professionals and industry to:
Analyse patient data to predict those at risk of developing MND
Uncover new therapies for MND, faster
Identify novel biomarkers to accelerate diagnosis and measure disease progression
Develop technology to improve the day-to-day quality of life for those living with MND
Some of our partnerships and initiatives
Preclinical Discovery and Development of Repurposed Drug Candidates for MND
Through LifeArc’s Translational Challenge in MND, this funding programme aims to boost drug repurposing in MND by investing at least £5 million in preclinical translation.
The MND Insights Group and community surveys
Uncovering the most important research questions and urgently address the needs of MND research, working with real experts who live with the condition.
The MND Translational Research Fund
A joint fund created by LifeArc and the Motor Neurone Disease Association (MND Association) and later joined by the My Name’5 Doddie Foundation.
Neurodegeneration
We also do broader work in neurodegeneration beyond MND.
Who to contact
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Paul Wright
Read bio: Paul Wright
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Yaa Adjei
Read bio: Yaa Adjei
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Roger Barker
Read bio: Roger Barker
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Derek Sheader
Read bio: Derek Sheader
Related stories
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News releasesNew partnership aims to develop clinical tools for motor neuron disease prognosis, monitoring, and drug development
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News releasesLifeArc and Kings College London team up to accelerate MND treatment development by driving systematic target validation
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News releasesLifeArc announces £5 million drug repurposing programme for motor neuron disease
See our other Translational Challenges
Chronic Respiratory Infection
Our vision is improved quality of life for those living with cystic fibrosis and bronchiectasis.
Global Health
Our vision is a world with affordable and accessible solutions to better understand, treat, and prevent infectious diseases.
Rare Disease
Our vision is an ecosystem working together to get discoveries and treatments to rare disease patients faster.
Childhood Cancer
Our vision is to drive life-changing innovations for children with cancer.
Contact us
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