Our strategy

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We develop and support life science to remove the barriers that prevent promising discoveries from reaching people with rare diseases and in global health.

As a self-funded organisation, we use our translational expertise to help people living with rare conditions and address some of the major infection-related threats facing human health. We call these areas ‘Translational Challenges.’ Our existing work spans motor neuron disease, global health, chronic respiratory infection, childhood cancer, and rare diseases. 

We collaborate with others already working in these areas to create better tests, treatments and cures by providing investment, expert scientific support and commercialisation advice. 

Our Translational Challenges

Each of our Translational Challenges targets a specific area or disease where research has great potential to deliver impact but lacks the translational infrastructure needed to bring discoveries to patients. We bring our science, advice and funding to these challenges, and also work closely with partners to tap into their expertise and capabilities. 

Motor Neuron Disease

Our vision is a world where motor neuron disease is preventable and treatable.

Human brain with abstract visualization of neuron activity

Chronic Respiratory Infection 

Our vision is improved quality of life for those living with cystic fibrosis and bronchiectasis. 

Global Health

Our vision is a world with affordable and accessible solutions to better understand, treat, and prevent infectious diseases. 

Mycobacterium tuberculosis bacteria, bacterial disease, 3d render

Rare Disease

Our vision is an ecosystem working together to get discoveries and treatments to rare disease patients faster. 

Blue chromosome DNA and gradually glowing flicker light matter chemical when camera moving closeup. Medical and Heredity genetic health concept. Technology science. 3D illustration rendering

Childhood Cancer

Our vision is to drive life-changing innovations for children with cancer.

Focus on the under-served patient

As an independent, self-funded charity, we can focus on finding solutions to medical challenges that may be overlooked due to their complexity, high-risk nature, or commercial uncertainty.

We’re focused on delivering what patients tell us they most need, whether that’s a transformative new drug, diagnostic, device or digital solution.

There are many organisations and researchers already doing incredible work in these areas. Often, we seek to partner with them. Sometimes, we simply act as a bridge between experts.

Creating a lasting impact  

We want to continue creating change for patients and building partnerships, long-term. 

That means having a plan in place around our financial sustainability. Part of that is in our funding structure, including our early venture funding.

But we’re also concentrating on developing and retaining talent and building our reputation as a leader in translational science.

See how we’re funded

Bird-eye view of a group of young business people playing games in a cheerful atmosphere during a break at work. Business, people, company
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