Our clinical trial collaborations

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We help partners navigate the clinical development journey.

We have a wide range of experience delivering clinical research projects. This includes clinical trial design and set-up (including regulatory and ethical approvals), supporting clinical trial delivery, or bringing experts together from our network of collaborators and charity partners.

See some of our clinical trial collaborations below.

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Research area
Phase
Intervention

Research area

Indication

Intervention

Trial Phase

  • ASM in CF: ANNE Sensor Monitoring in Cystic Fibrosis

    Research area:

    Chronic respiratory infection

    Disease:

    Cystic Fibrosis

    Intervention:

    Device – Software/AI

    Phase:

    N/A*

    Funding awarded to

    Papworth Hospital NHS Foundation Trust

    Public registration details (where available)

    NCT05941832

  • Bronch-EX: Early Detection of Pulmonary Exacerbations in Non-cystic Fibrosis Bronchiectasis

    Research area:

    Chronic respiratory infection

    Disease:

    Non-cystic fibrosis bronchiectasis

    Intervention:

    Device – software/AI

    Phase:

    N/A*

    Funding awarded to

    Papworth Hospital NHS Foundation Trust

    Public registration details (where available)

    NCT06151366

  • EMBARC-AIRNET: The EMBARC Anti-Inflammatory Repurposing Network

    Research area:

    Chronic respiratory infection

    Disease:

    Bronchiectasis

    Intervention:

    Therapeutics – Small molecules

    Phase:

    Phase II

    Funding awarded to

    University of Dundee

    Public registration details (where available)

    ISRCTN17596258

  • FARGO: FAecal Microbiota Transplantation in primaRy sclerosinG chOlangitis

    Research area:

    Rare disease

    Disease:

    Primary sclerosing cholangitis

    Intervention:

    Therapeutics – large molecules/biologics

    Phase:

    Phase IIa

    Funding awarded to

    University of Birmingham

    Public registration details (where available)

    NCT06286709

  • Gene Therapy with Modified Autologous Hematopoietic Stem Cells for Patients with Mucopolysaccharidosis Type II

    Research area:

    Rare disease

    Disease:

    Mucopolysaccharidosis type II

    Intervention:

    Therapeutics – ATMP

    Phase:

    Phase I/II

    Funding awarded to

    University of Manchester

    Public registration details (where available)

    NCT05665166

  • DefINe: A trial to test the use of deferiprone in people with neuroferritinopathy

    Research area:

    Rare disease

    Disease:

    Neuroferritinopathy

    Intervention:

    Therapeutics – small molecules

    Phase:

    Phase II

    Funding awarded to

    University of Cambridge

    Public registration details (where available)

    ISRCTN15571700

  • TIME study: TB DIagnosis and Monitoring Evaluation

    Research area:

    Global health

    Disease:

    Pulmonary tuberculosis

    Intervention:

    Device – In vitro diagnostic

    Phase:

    N/A*

    Funding awarded to

    Internal LifeArc project

  • TIARA: Autologous Tregs for Aplastic Anaemia

    Research area:

    Rare disease

    Disease:

    Aplastic anaemia

    Intervention:

    Therapeutics – ATMP

    Phase:

    Phase I

    Funding awarded to

    King’s College London

    Public registration details (where available)

    NCT05386264

  • Prospective evaluation of KARSARC -a gene expression-based risk classifier for patients with soft tissue sarcomas treated with pazopanib

    Research area:

    Rare disease

    Disease:

    Soft tissue sarcomas

    Intervention:

    Device – In vitro diagnostic

    Phase:

    N/A*

    Funding awarded to

    The Institute of Cancer Research

  • The CADET Trial: The Children’s Adaptive Deep brain stimulation for Epilepsy Trial

    Research area:

    Rare disease

    Disease:

    Lennox-Gastaut syndrome

    Intervention:

    Device – medical device

    Phase:

    N/A*

    Funding awarded to

    University College London and GOSH

    Public registration details (where available)

    NCT06924086

  • STOPFOP: Saracatinib trial TO Prevent FOP

    Research area:

    Rare disease

    Disease:

    Fibrodysplasia Ossificans Progressiva (FOP)

    Intervention:

    Therapeutics – small molecules

    Phase:

    Phase II

    Funding awarded to

    University of Oxford

    Public registration details (where available)

    NCT04307953

  • Phase II Study of a Novel Vitamin Metabolite (CoA-Z) for Pantothenate Kinase Associated Neurodegeneration

    Research area:

    Rare disease

    Disease:

    Pantothenate kinase associated neurodegeneration

    Intervention:

    Therapeutics – small molecules

    Phase:

    Phase II

    Funding awarded to

    University College London Great Ormond’s Street Hospital

*N/A is used for clinical studies which do not fit into the defined interventional trial phases. For example, those which are assessing the clinical performance of diagnostic devices or observational studies.

Disclaimers

The information contained within these tables is compiled from study reports provided to LifeArc and public registries. This may not reflect the live status of a study.

We are not in a position to directly recruit people onto clinical trials. Please ask a healthcare professional or a patient organisation if they know of any clinical trials that you may be eligible to join.

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