Our clinical trial collaborations

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We help partners navigate the clinical development journey.

We have a wide range of experience delivering clinical research projects. This includes clinical trial design and set-up (including regulatory and ethical approvals), supporting clinical trial delivery, or bringing experts together from our network of collaborators and charity partners.

See some of our clinical trial collaborations below.

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Research area
Phase
Intervention

Research area

Indication

Intervention

Trial Phase

  • CognoMND: An automated cognitive and behaviour assessment tool based on language (utilising automated speech recognition and machine learning)

    Research area:

    Motor neuron disease & rare dementias

    Disease:

    Motor neuron disease

    Intervention:

    Device – Software/AI

    Phase:

    N/A*

    Funding awarded to

    Prof Christopher McDermott, University of Sheffield

    Visit this trial’s project page
  • Elpida Therapeutics: Accelerating gene therapies for ultra‑rare neurodegenerative diseases

    Research area:

    Rare disease

    Disease:

    Spastic Paraplegia type 50 (SPG50), Neuronal ceroid lipofuscinosis 7 (CLN7 Batten disease), Charcot–Marie–Tooth disease type 4J (CMT4J).

    Intervention:

    Therapeutics – ATMP

    Phase:

    Funding awarded to

    Elpida Therapeutics

    Visit this trial’s project page
  • Investigating a novel gene therapy for CTLA-4 insufficiency

    Research area:

    Rare disease

    Disease:

    CTLA-4 insufficiency

    Intervention:

    Therapeutics – ATMP

    Phase:

    Funding awarded to

    Dr Thomas Fox, University College London

    Visit this trial’s project page
  • Evaluation of the effect of intranasal insulin on development and behaviour in Phelan-McDermid syndrome

    Research area:

    Rare disease

    Disease:

    Phelan-McDermid Syndrome

    Intervention:

    Therapeutics – Small molecules

    Phase:

    Funding awarded to

    Andre Strydom, King’s College London

    Visit this trial’s project page
  • Advancing Repurposed Therapeutics for Epidermolysis Bullosa (ART-EB)

    Research area:

    Rare disease

    Disease:

    Epidermolysis Bullosa

    Intervention:

    Therapeutics – large molecules/biologics

    Phase:

    Phase II/III

    Funding awarded to

    Dr Su Lwin, Kings College London

    Visit this trial’s project page
  • D-Scape: Dengue Shock Classification and Prediction Wearable

    Research area:

    Global health

    Disease:

    Severe dengue haemorrhagic fever (DHF)

    Intervention:

    Device – Medical device

    Phase:

    N/A*

    Funding awarded to

    Imperial College London and OUCRU

    Visit this trial’s project page
  • The use of CARBALIVE in the treatment of cholestatic liver disease

    Research area:

    Rare disease

    Disease:

    Cholestatic liver disease

    Intervention:

    Device

    Phase:

    Phase II

    Public registration details (where available)

    ISRCTN16819837

  • ACE-CF: Detection of respiratory exacerbations in adults with cystic fibrosis using artificial intelligence

    Research area:

    Chronic & rare respiratory

    Disease:

    Cystic fibrosis

    Intervention:

    Device – Software/AI

    Phase:

    N/A*

    Funding awarded to

    Papworth Hospital NHS Foundation Trust

    Public registration details (where available)

    ISRCTN27664426

    Visit this trial’s project page
  • ASPIRE: The Antibiotic Stewardship Programme through Innovation, Research, and Education

    Research area:

    Global health, Antimicrobial resistance

    Disease:

    Antimicrobial resistance

    Intervention:

    Device – Software/AI

    Phase:

    NA*

    Funding awarded to

    ReAct

    Public registration details (where available)

    ASPIRE – National Action Plans – ReAct

    Visit this trial’s project page
  • EXPErimental medicine Route To Success in Amyotrophic Lateral Sclerosis (EXPERTS-ALS)

    Research area:

    Motor neuron disease & rare dementias

    Disease:

    Amyotrophic Lateral Sclerosis (ALS)

    Intervention:

    Therapeutics – Small molecules

    Phase:

    Phase II

    Funding awarded to

    Sheffield Teaching Hospitals NHS Foundation Trust

    Public registration details (where available)

    ISRCTN15525855

  • MinderCare – Translational research and digitally enabled care

    Research area:

    Motor neuron disease & rare dementias

    Disease:

    Dementia

    Intervention:

    Device – Medical device

    Phase:

    N/A*

    Funding awarded to

    Imperial College London & Imperial College Healthcare NHS Trust

    Public registration details (where available)

    ISRCTN14997677

    Visit this trial’s project page
  • Bronch-EX: Early Detection of Pulmonary Exacerbations in Non-cystic Fibrosis Bronchiectasis

    Research area:

    Chronic & rare respiratory

    Disease:

    Non-cystic fibrosis bronchiectasis

    Intervention:

    Device – software/AI

    Phase:

    N/A*

    Funding awarded to

    Papworth Hospital NHS Foundation Trust

    Public registration details (where available)

    NCT06151366

    Visit this trial’s project page

*N/A is used for clinical studies which do not fit into the defined interventional trial phases. For example, those which are assessing the clinical performance of diagnostic devices or observational studies.

Disclaimers

The information contained within these tables is compiled from study reports provided to LifeArc and public registries. This may not reflect the live status of a study.

We are not in a position to directly recruit people onto clinical trials. Please ask a healthcare professional or a patient organisation if they know of any clinical trials that you may be eligible to join.

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