Our clinical trial collaborations

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We help partners navigate the clinical development journey.

We have a wide range of experience delivering clinical research projects. This includes clinical trial design and set-up (including regulatory and ethical approvals), supporting clinical trial delivery, or bringing experts together from our network of collaborators and charity partners.

See some of our clinical trial collaborations below.

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Research area
Phase
Intervention

Research area

Indication

Intervention

Trial Phase

  • The use of CARBALIVE in the treatment of cholestatic liver disease

    Research area:

    Rare disease

    Disease:

    Cholestatic liver disease

    Intervention:

    Device

    Phase:

    Phase II

    Public registration details (where available)

    ISRCTN16819837

  • ACE-CF: Detection of respiratory exacerbations in adults with cystic fibrosis using artificial intelligence

    Research area:

    Chronic & rare respiratory

    Disease:

    Cystic fibrosis

    Intervention:

    Device – Software/AI

    Phase:

    N/A*

    Funding awarded to

    Papworth Hospital NHS Foundation Trust

    Public registration details (where available)

    ISRCTN27664426

  • ASPIRE: The Antibiotic Stewardship Programme through Innovation, Research, and Education

    Research area:

    Global health, Antimicrobial resistance

    Disease:

    Antimicrobial resistance

    Intervention:

    Device – Software/AI

    Phase:

    NA*

    Funding awarded to

    ReAct

    Public registration details (where available)

    ASPIRE – National Action Plans – ReAct

    Visit this trial’s project page
  • EXPErimental medicine Route To Success in Amyotrophic Lateral Sclerosis (EXPERTS-ALS)

    Research area:

    Motor neuron disease & rare dementias

    Disease:

    Amyotrophic Lateral Sclerosis (ALS)

    Intervention:

    Therapeutics – Small molecules

    Phase:

    Phase II

    Funding awarded to

    Sheffield Teaching Hospitals NHS Foundation Trust

    Public registration details (where available)

    ISRCTN15525855

  • MinderCare – Translational research and digitally enabled care

    Research area:

    Motor neuron disease & rare dementias

    Disease:

    Dementia

    Intervention:

    Device – Medical device

    Phase:

    N/A*

    Funding awarded to

    Imperial College London & Imperial College Healthcare NHS Trust

    Public registration details (where available)

    ISRCTN14997677

    Visit this trial’s project page
  • ASM in CF: ANNE Sensor Monitoring in Cystic Fibrosis

    Research area:

    Chronic & rare respiratory

    Disease:

    Cystic fibrosis

    Intervention:

    Device – Software/AI

    Phase:

    N/A*

    Funding awarded to

    Papworth Hospital NHS Foundation Trust

    Public registration details (where available)

    NCT05941832

  • Bronch-EX: Early Detection of Pulmonary Exacerbations in Non-cystic Fibrosis Bronchiectasis

    Research area:

    Chronic & rare respiratory

    Disease:

    Non-cystic fibrosis bronchiectasis

    Intervention:

    Device – software/AI

    Phase:

    N/A*

    Funding awarded to

    Papworth Hospital NHS Foundation Trust

    Public registration details (where available)

    NCT06151366

  • AIR-NET: Testing anti-inflammatories for the treatment of bronchiectasis

    Research area:

    Chronic & rare respiratory

    Disease:

    Bronchiectasis

    Intervention:

    Therapeutics – Small molecules

    Phase:

    Phase II

    Funding awarded to

    University of Dundee

    Public registration details (where available)

    ISRCTN17596258

    Visit this trial’s project page
  • FARGO: FAecal Microbiota Transplantation in primaRy sclerosinG chOlangitis

    Research area:

    Rare disease

    Disease:

    Primary sclerosing cholangitis

    Intervention:

    Therapeutics – large molecules/biologics

    Phase:

    Phase IIa

    Funding awarded to

    University of Birmingham

    Public registration details (where available)

    NCT06286709

  • Gene Therapy with Modified Autologous Hematopoietic Stem Cells for Patients with Mucopolysaccharidosis Type II

    Research area:

    Rare disease

    Disease:

    Mucopolysaccharidosis type II

    Intervention:

    Therapeutics – ATMP

    Phase:

    Phase I/II

    Funding awarded to

    University of Manchester

    Public registration details (where available)

    NCT05665166

  • DefINe: A trial to test the use of deferiprone in people with neuroferritinopathy

    Research area:

    Rare disease

    Disease:

    Neuroferritinopathy

    Intervention:

    Therapeutics – small molecules

    Phase:

    Phase II

    Funding awarded to

    University of Cambridge

    Public registration details (where available)

    ISRCTN15571700

    Visit this trial’s project page
  • TIME study: TB DIagnosis and Monitoring Evaluation

    Research area:

    Global health

    Disease:

    Pulmonary tuberculosis

    Intervention:

    Device – In vitro diagnostic

    Phase:

    N/A*

    Funding awarded to

    Internal LifeArc project

    Visit this trial’s project page

*N/A is used for clinical studies which do not fit into the defined interventional trial phases. For example, those which are assessing the clinical performance of diagnostic devices or observational studies.

Disclaimers

The information contained within these tables is compiled from study reports provided to LifeArc and public registries. This may not reflect the live status of a study.

We are not in a position to directly recruit people onto clinical trials. Please ask a healthcare professional or a patient organisation if they know of any clinical trials that you may be eligible to join.

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