Job Title: Senior Scientist, Antibody Discovery
Location: London
Job Type: Full-time, permanent
Are you passionate about making life science life changing and delivering impact for patients? We want to hear from you.
About the role:
As Senior Scientist, you will primarily run multi-marker single B-cell sorting experiments, including complex data analysis to support our internal and external antibody discovery projects.
Working with our national and international collaborators and our internal scientist teams, you will work to deliver the next generation of therapeutics across a wide range of disease areas.
Key responsibilities:
- Independently design, run and analyse single-B-cell sorting experiments for our portfolio of antibody discovery projects.
- Independently design and apply multi-colour cytometry panels and selection strategies guided by our established SOPs.
- Perform in-depth analysis of flow cytometric data, including clear visualisation and presentation of large data sets.
- Summarise, interpret and if required, troubleshoot the results and clearly present the findings and conclusions.
(Essential) experience required:
- Proven experience in single-cell fluorescent activated cell sorting (FACS)
- Familiarity with various flow cytometry data analysis software (e.g. FlowJo and FACS Diva)
- In-depth technical knowledge of flow cytometry standards, protocols, best practices, troubleshooting and sorting instrumentation
- Background knowledge and experience in immunology
(Essential) Education:
- PhD in a relevant branch of biosciences or highly relevant extensive laboratory experience in cellular immunology including FACS
Desirable:
- Experience in an academic core facility or industry, including sorting a wide variety of cell types, preferably in connection with B-cells and in vivo-based antibody discovery strategies
- Experience with BD FACS Aria Fusion
- Experience preparing immune cells from tissues
- Specific experience in B-cell and/or plasma cell isolation techniques
Skills & abilities:
- Strong attention to detail with the ability to solve problems and act as a critical and analytical thinker
- Ability to work well with others and under time pressure
- Excellent communication skills – both verbal and written
About us:
LifeArc is a not-for-profit life science organisation, leading the way for change in rare diseases in the UK and supporting promising initiatives in global health. We seek out research in areas of unmet need that has great potential, providing support to help it become breakthroughs that change lives.
What we can offer you:
Focused on finding life changing solutions for underserved patients, our people thrive in an inclusive, and supportive environment that prioritises their health and wellbeing. Our multidisciplinary approach guarantees our people growth opportunities, while our culture of innovation and collaboration drives the impact we make delivering on our purpose of ‘putting patients at the centre of everything we do’.
LifeArc is committed to making our recruitment practices as inclusive as possible and developing a culture that values differences. As a Disability Confident Employer, we guarantee an interview to candidates with a disability or long-term health condition who meet the essential criteria for the role.
Please note that in certain situations, such as high volumes of applications, it may not be practical to interview all eligible candidates. In these cases, we may need to select those who best meet the essential criteria. (At LifeArc, the Disability Confident Scheme’s ‘minimum criteria’ is referred to as ‘essential criteria’).
Salary will be determined by qualifications and experience along with other exceptional benefits. Because we understand everyone has different requirements, our flexible benefits allow you to choose those which are important to you. Our pension scheme offers employer contributions of up to 12%, private health insurance, and annual leave of 31 days PLUS bank holidays.
Don’t meet every single requirement? Studies have shown that women and people from minority ethnic backgrounds, for example, are less likely to apply to jobs unless they meet every single qualification. At LifeArc we are dedicated to building a diverse, inclusive, and authentic workplace, so whatever your background or lived experience, if you’re excited about this role but your experience doesn’t align perfectly with every qualification in the job description, we encourage you to apply anyway. Our top priority is finding the best candidate, and you may be just right for this or other roles.
We all have potential. At LifeArc, you’ll discover what you can really do with it.
Agencies: We will only work with recruitment partners on our preferred supplier list and will not engage with speculative CVs submitted.
