Funding: Partnering with Great Ormond Street Hospital Charity (GOSH Charity) to deliver research grants for paediatric rare diseases
With GOSH Charity, we are providing funding for projects on the translational pathway to improve the prevention, diagnosis, prognosis, or treatment of paediatric rare diseases
Application timeline
| Application step | Date |
|---|---|
| Open date for outline applications | 13 January 2025 |
| Pre-application webinar | 3 February 2025 |
| Closing date for submission of outline applications | 12 pm 3 April 2025 |
| Applicants informed of the outcome of their applications | Early May 2025 |
| Shortlisted applicants invited to submit a full application | Late June 2025 |
About the grants
With GOSH charity, we are inviting translational, milestone-driven applications which aim to:
- improve the prevention, diagnosis, prognosis, or treatment of rare disease.
- develop research tools that increase the efficiency of developing interventions in rare disease.
The scheme is designed to support applications on the translational pathway with the expectation that researchers will continue to develop their therapy/diagnostic after GOSH Charity/LifeArc funding, either by securing further funding from external translational schemes or partnering with/licensing to industry.
Funding available
This funding scheme is currently available
This funding scheme is now open for outline applications. For more information about this funding scheme, click here
Available funding
There is a total of £1 million available for this call. From this, we expect to award 2 to 3 high-quality projects with a minimum value of £250k each, for up to three years.
Application eligibility
Projects must be led by active academic research professionals based at an eligible Higher Education Institution in the UK. Collaborations with industry and other academic partners are encouraged where relevant to the project. Lead applicants may only submit one application per round.
Applications should:
- address a rare disease medical need
- have a strong scientific rationale
- be a target-driven, milestone-oriented project with a credible delivery plan
- have a clear route to patient
The following activities are eligible for support:
- pre-clinical testing of novel therapeutic entities in vitro or in vivo
- pre-clinical validation for repurposed therapeutics
- early-phase clinical trials of novel therapeutic entities (phases 1/2)
- clinical trials of existing therapeutics repurposed for a new indication
- developing and testing novel devices
- developing and testing diagnostics (including biomarker validation)
All modalities of intervention are eligible for support from the scheme, including small molecules, peptides, antibodies, vaccines, regenerative medicine, cell and gene therapy, devices, surgical techniques and psychological approaches.
You can download additional guidance on the translational research accelerator grants here.
Register for our webinar to receive pre-application support
We are hosting a webinar with GOSH Charity to provide candidates with further information on the funding scheme on 3 February 2025, 12:00 – 13:30.
Application process
This funding scheme is now open for outline applications! The deadline for outline submission is 12 pm, Thursday 3 April 2025.
This is a two-stage application process:
- Applicants are required to submit an outline application form through GOSH Charity’s online application portal which will be shortlisted by GOSH Charity’s Research Assessment Panel.
- Shortlisted applicants will then be invited to submit a full application which will undergo external peer review, due diligence review by LifeArc’s Opportunity Assessment Group, and further review by GOSH Charity’s Research Assessment Panel, and GOSH Charity’s Research Patient Insight Panel.
If you have any questions before applying, please contact the GOSH Charity grants team by emailing grants@gosh.org. Including questions around eligibility of the proposed project.
