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MRC Reagents Catalogue

The MRC aims to make the valuable research tools and reagents generated by MRC scientists accessible to the wider scientific community. LifeArc manages these on behalf of the MRC for academic research use and commercial licensing. For academic research, we can help get a standard Material Transfer Agreement (MTA) in place. For commercial purposes, materials are licensed on a non-exclusive basis for sale as catalogue reagents, in-house R&D purposes, and other commercial applications. Once a license or MTA is in place, materials will be released from our partner repositories or academics labs.

Browse the catalogue of available reagents and research tools below. Please click on the item of interest to find out more and submit an enquiry.

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Anti-fish CD45-like PTPase monoclonal antibody

Hybridoma

Anti-fish CD45-like PTPase monoclonal antibody

Track code A857/3347

Type Hybridoma

Clone FL.1

Reactivity Oreochromis spilurus; Oreochromis mossambicus

IsoType IgG2b

Host Mouse

Description Reacts specifically with a membrane protein expressed exclusively by macrophages, microglia and other leukocytes in Oreochromis spilurus and O. mossambicus. The protein that reacts with has the enzymatic characteristics of a protein tyrosine phosphatase and could be the fish equivalent of mammalian CD45.

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Anti-fish 7.4.C4 monoclonal antibody

Hybridoma

Anti-fish 7.4.C4 monoclonal antibody

Track code A857/3338

Type Hybridoma

Clone 7.4.C4

Reactivity Zebrafish; Oreochromis mosambicus

IsoType IgG1κ

Host Mouse

Description The antibody is directed against cell surface components expressed on leukocytes, red blood cells and vascular endothelial cells of fish.

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Anti-human SIRP beta monoclonal antibody

Hybridoma

Anti-human SIRP beta monoclonal antibody

Track code A857/3251

Type Hybridoma

Clone OX137

Reactivity Human

IsoType IgG

Host Mouse

Description Recognises one allele of human SIRP beta (allele 2) but not SIRP alpha or SIRP beta allele 1

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Anti-N-ethymaleimide monoclonal antibody

Hybridoma

Anti-N-ethymaleimide monoclonal antibody

Track code A857/3250

Type Hybridoma

Clone OX133

Reactivity n/a

IsoType IgG

Host Mouse

Description Recognises protein-bound N-ethylmaleimide (NEM) for the identification of reduced disulfide bonds in proteins. Target species independent.

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Anti-human SIRP beta 1

Hybridoma

Anti-human SIRP beta 1

Track code A857/3249

Type Hybridoma

Clone OX130

Reactivity Human

IsoType IgG

Host Mouse

Description Recognises human SIRP beta 1 but cross-reacts with SIRP alpha from one allele

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Anti-human CD6.1 monoclonal antibody

Hybridoma

Anti-human CD6.1 monoclonal antibody

Track code A857/3247

Type Hybridoma

Clone OX126

Reactivity Human

IsoType IgG1

Host Mouse

Description Recognises CD6.1, blocks function

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Anti-human CD6 domain 3 monoclonal antibody

Hybridoma

Anti-human CD6 domain 3 monoclonal antibody

Track code A857/3246

Type Hybridoma

Clone OX125

Reactivity Human

IsoType IgG2b

Host Mouse

Description Recognises CD6 domain 3

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Anti-human CD6 domain 3 monoclonal antibody

Hybridoma

Anti-human CD6 domain 3 monoclonal antibody

Track code A857/3245

Type Hybridoma

Clone OX124

Reactivity Human

IsoType IgG1

Host Mouse

Description Recognises CD6 domain 3

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Anti-mouse CD147 dom-o monoclonal antibody

Hybridoma

Anti-mouse CD147 dom-o monoclonal antibody

Track code A857/3014

Type Hybridoma

Clone OX115

Reactivity Mouse

IsoType IgG2a

Host Rat

Description Recognises an alternatively spliced domain of mouse CD147

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Anti-human CD200R monoclonal antibody

Hybridoma

Anti-human CD200R monoclonal antibody

Track code A857/3013

Type Hybridoma

Clone OX109

Reactivity Human

IsoType IgG2a

Host Mouse

Description Recognises CD200R

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Anti-mouse CD200RLc monoclonal antibody

Hybridoma

Anti-mouse CD200RLc monoclonal antibody

Track code A857/2953

Type Hybridoma

Clone OX132

Reactivity Mouse

IsoType IgG

Host Rat

Description Recognises CD200R Lc, an activating variant of CD200R present in some mouse strains

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Anti-mouse CD200R monoclonal antibody

Hybridoma

Anti-mouse CD200R monoclonal antibody

Track code A857/2952

Type Hybridoma

Clone OX131

Reactivity Mouse

IsoType IgG1

Host Rat

Description Recognises both common alleles of CD200R and also cross reacts on CD200RLe present in some mouse strains

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Anti-rat IgG2b monoclonal antibody

Hybridoma

Anti-rat IgG2b monoclonal antibody

Track code A857/2926

Type Hybridoma

Clone OX14

Reactivity Rat

IsoType IgG1

Host Mouse

Description Recognises an antigen on the rat IgG2b molecule

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Anti-mouse CD6 domain 3 monoclonal antibody

Hybridoma

Anti-mouse CD6 domain 3 monoclonal antibody

Track code A857/2864

Type Hybridoma

Clone OX129

Reactivity Mouse

IsoType IgG2a

Host Rat

Description Recognises mouse CD6 domain 3

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Anti-human HLA monoclonal antibody

Hybridoma

Anti-human HLA monoclonal antibody

Track code A857/0673

Type Hybridoma

Clone W6/32HK

Reactivity Human

IsoType IgG2a

Host Mouse

Description This is an inactive clone derived from the hybridoma line W6/32. The antibody selected contains the specific heavy chain, but it is in association with the myeloma light chain.

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Anti-human Polycystin-1 monoclonal Antibody

Hybridoma

Anti-human Polycystin-1 monoclonal Antibody

Track code A857/0255

Type Hybridoma

Clone 7.00E+12

Reactivity Human

IsoType IgG1κ

Host Mouse

Description Recognises the N-terminal domain of Polycystin-1 encoded by gene PKD1

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Anti-rat MHC Class II RT1D (Ia-E) monoclonal antibody

Hybridoma

Anti-rat MHC Class II RT1D (Ia-E) monoclonal antibody

Track code A857/0236

Type Hybridoma

Clone OX17

Reactivity Rat

IsoType IgG1

Host Mouse

Description Recognises RT1D, a non-polymorphic Ia epitope present on B cells, but not T cells from lymph node or thoracic duct lymph. It does not bind to thymocytes or erythrocytes.

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Anti-rat thymocyte monoclonal antibody

Hybridoma

Anti-rat thymocyte monoclonal antibody

Track code A857/0206

Type Hybridoma

Clone W3/15

Reactivity Rat

IsoType IgG1

Host Mouse

Description Reacts with thymocytes, bone marrow (erythroid)

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Anti-myosin monoclonal antibody

Hybridoma

Anti-myosin monoclonal antibody

Track code A857/0180

Type Hybridoma

Clone A4.1519

Reactivity Rat; Mouse; Human

IsoType IgM

Host Mouse

Description Recognises myosin heavy chain fast IIA (MYH2) and some cross-reactivity to IIB

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Anti-human SIRP gamma monoclonal antibody

Hybridoma

Anti-human SIRP gamma monoclonal antibody

Track code A857/0178

Type Hybridoma

Clone OX119

Reactivity Human

IsoType IgG1

Host Mouse

Description Recognises SIRP gamma (CD172g) and blocks activity

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