Lead optimisation
Hit to lead
Assay Development
Therapeutic area
  • Cancer

Project Aim

To identify potent ULK1 inhibitors of the mTOR induced autophagy pathway


Blocking ULK1, as the main arbiter of autophagy, will result in enhanced tumour cell death in combination with chemo and radiotherapy

Target Class

Enzyme (kinase)


Small molecule

Current Status

Hit to Lead with preliminary in-vivo data

Intellectual Property

Opportunity to create a protective IPR portfolio


Licence or shared risk collaboration

Key Contact

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