Therapeutic area
Background info
Indication
Advantages
Intellectual property
Owner/lead
What the technology does
SiR (Self-inactivating rabies vector) can deliver genome editing machinery to either a defined neural networks or the whole CNS.
Advantage
Pan-CNS infectivity of the vector, through polysynaptic movement, allows for disorders affecting the whole CNS to be treated through genome editing. Alternatively monosynaptic movement can limit vector distribution and genome editing to a defined area.
Main application field
CNS disorders
Modality
Genome engineering
Status
Technology ready for evaluation and licencing
Intellectual Property
Patent application filed May 2017 (GB1706945.1)
Offering
Exclusive or non-exclusive licence