Lead optimisation
Hit to lead
Assay Development
Therapeutic area
  • Cancer

Project Aim

To develop first in class cancer therapeutic agents targeting PAICS


Potent, selective inhibitor of PAICS, a key enzyme in cancer metabolism

Target Class

Enzyme (Carboxylase/synthetase)

Therapeutic Area

Cancer (esp. metastasis and/or growth)


Small molecule

Current Status

Lead series established

Intellectual Property

Patent application filed December 2016


Licence or collaboration for preclinical / clinical development

Key Contact

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