Matriptase, a small molecule inhibitor

PROJECT STAGE

Lead optimisation

Hit to lead

Screening

Assay Development

Therapeutic area

To develop a small molecule inhibitor of Matriptase for osteoarthritis

Disease-modifying anti-osteoarthritis therapeutic agent with the potential to address pathophysiology

Enzyme (peptidase)

Osteoarthritis

Small molecule

Lead series

Opportunity to create a protective IPR portfolio

Licence for pre-clinical/clinical development

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