Lead optimisation
Hit to lead
Assay Development
Therapeutic area
  • Inflammation
  • Osteoarthritis

Project Aim

To develop a small molecule inhibitor of Matriptase for osteoarthritis


Disease-modifying anti-osteoarthritis therapeutic agent with the potential to address pathophysiology

Target Class

Enzyme (peptidase)

Therapeutic Area



Small molecule

Current Status

Lead series

Intellectual Property

Opportunity to create a protective IPR portfolio


Licence for pre-clinical/clinical development

Key Contact

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