What the technology does
LITA is a novel nanoparticle containing short-chain fatty acids, particularly acetate, that alters the metabolic process leading to cancer cell death
These nanoparticle are concentrated in tumour cells and by release of acetate change the metabolism in the cancer cell. Cancer cells are vulnerable to metabolic interruption and these nanoparticle seem to selectively cause degradation of cancer cell mitochondria. This results in selective cell death. In fat cells these nanoparticles cause an increase in the number of mitochondria resulting in the “browning” of fat cells which may have potential therapeutic effects.
Main application field
Cancer treatment, potential uses in fatty liver disease and other inflammatory indications.
Technology ready for evaluation and licence.
Patents filed in Europe, USA, China, Japan, Australia, Canada, Hong Kong WO2014/033453
Exclusive or non-exclusive licences are available