PROJECT STAGE
Lead optimisation
Hit to lead
Screening
Assay Development
Therapeutic area
  • Inflammation

What the technology does

A humanised monoclonal antibody against the IL-25 receptor IL-17BR that shows activity in models of lung fibrosis, colitis and asthma

Advantage

Affinities of <1nM, desirable biophysical properties for a therapeutic drug, potential for therapeutic benefits in multiple diseases involving type 2 immune responses

Main application field

Inflammation

Usage

Therapeutic – antibody

Status

Lead optimisation

Intellectual Property

Patents granted in Japan (JP20120504066T), United States (US20130056559), Australia (AU20100233535), Europe (EP20100712110), China (CN201080022541) and Hong Kong (HK20120111452). Published in Canada (CA20102757104) and India (IN2011DN08006).

Offering

Collaboration or exclusive licence

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