Clinical trials

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We can help you progress healthcare innovations through clinical trials and into clinical use.

Whether it’s a therapy, diagnostic, device or other medical technology, we can help you navigate the clinical development journey and increase the likelihood of reaching patients.

Our experienced clinical team offers personalised development strategies and planning to support you across all aspects of clinical affairs, including trial design and operations, regulatory compliance, and stakeholder engagement with patients and healthcare professionals.

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Our areas of expertise

Clinical trials we’re supporting

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Phase
Intervention

Research area

Indication

Intervention

Trial Phase

  • Research area:

    Chronic respiratory infection

    Disease:

    Cystic Fibrosis

    Intervention:

    Device – Software/AI

    Phase:

    N/A*

    ASM in CF: ANNE Sensor Monitoring in Cystic Fibrosis

    Intervention

    Device – Software/AI

    Funding awarded to

    Papworth Hospital NHS Foundation Trust

    Public registration details (where available)

    NCT05941832

    Planned trial start and expected end date

    TBC

  • Research area:

    Chronic respiratory infection

    Disease:

    Non-cystic fibrosis bronchiectasis

    Intervention:

    Device – software/AI

    Phase:

    N/A*

    Bronch-EX: Early Detection of Pulmonary Exacerbations in Non-cystic Fibrosis Bronchiectasis

    Intervention

    Device – software/AI

    Funding awarded to

    Papworth Hospital NHS Foundation Trust

    Public registration details (where available)

    NCT06151366

    Planned trial start and expected end date

    TBC

  • Research area:

    Chronic respiratory infection

    Disease:

    Bronchiectasis

    Intervention:

    Therapeutics – Small molecules

    Phase:

    Phase II

    EMBARC-AIRNET: The EMBARC Anti-Inflammatory Repurposing Network

    Intervention

    Therapeutics – Small molecules

    Funding awarded to

    University of Dundee

    Public registration details (where available)

    ISRCTN17596258

    Planned trial start and expected end date

    July 2024 to February 2027

  • Research area:

    Rare disease

    Disease:

    Primary sclerosing cholangitis

    Intervention:

    Therapeutics – large molecules/biologics

    Phase:

    Phase IIa

    FARGO: FAecal Microbiota Transplantation in primaRy sclerosinG chOlangitis

    Intervention

    Therapeutics – large molecules/biologics

    Funding awarded to

    University of Birmingham

    Public registration details (where available)

    NCT06286709

    Planned trial start and expected end date

    March 2024 to July 2026

  • Research area:

    Rare disease

    Disease:

    Mucopolysaccharidosis type II

    Intervention:

    Therapeutics – ATMP

    Phase:

    Phase I/II

    Gene Therapy with Modified Autologous Hematopoietic Stem Cells for Patients with Mucopolysaccharidosis Type II

    Intervention

    Therapeutics – ATMP

    Funding awarded to

    University of Manchester

    Public registration details (where available)

    NCT05665166

    Planned trial start and expected end date

    June 2023 to September 2027

  • Research area:

    Rare disease

    Disease:

    Neuroferritinopathy

    Intervention:

    Therapeutics – small molecules

    Phase:

    Phase II

    DefINe: A trial to test the use of deferiprone in people with neuroferritinopathy

    Intervention

    Therapeutics – small molecules

    Funding awarded to

    University of Cambridge

    Public registration details (where available)

    ISRCTN15571700

    Planned trial start and expected end date

    April 2023 to February 2026

  • Research area:

    Motor neuron disease

    Disease:

    Amyotrophic lateral sclerosis

    Intervention:

    Therapeutics – Small molecules

    Phase:

    Phase II

    EXPERTS-ALS: EXPErimental medicine Route To Success in Amyotrophic Lateral Sclerosis

    Intervention

    Therapeutics – Small molecules

    Funding awarded to

    University of Sheffield, University of Oxford

    Public registration details (where available)

    ISRCTN15525855

    Planned trial start and expected end date

    February 2024 to September 2028

  • Research area:

    Global health

    Disease:

    Pulmonary tuberculosis

    Intervention:

    Device – In vitro diagnostic

    Phase:

    N/A*

    TIME study: TB DIagnosis and Monitoring Evaluation

    Intervention

    Device – In vitro diagnostic

    Funding awarded to

    Internal LifeArc project

    Planned trial start and expected end date

    February 2023 to October 2024

  • Research area:

    Rare disease

    Disease:

    Aplastic anaemia

    Intervention:

    Therapeutics – ATMP

    Phase:

    Phase I

    TIARA: Autologous Tregs for Aplastic Anaemia

    Intervention

    Therapeutics – ATMP

    Funding awarded to

    King’s College London

    Public registration details (where available)

    NCT05386264

    Planned trial start and expected end date

    July 2022 to September 2025

  • Research area:

    Rare disease

    Disease:

    Soft tissue sarcomas

    Intervention:

    Device – In vitro diagnostic

    Phase:

    N/A*

    Prospective evaluation of KARSARC -a gene expression-based risk classifier for patients with soft tissue sarcomas treated with pazopanib

    Intervention

    Device – In vitro diagnostic

    Funding awarded to

    The Institute of Cancer Research

    Planned trial start and expected end date

    July 2022 to April 2027

  • Research area:

    Rare disease

    Disease:

    Lennox-Gastaut syndrome

    Intervention:

    Device – medical device

    Phase:

    Phase II

    CADET trial

    Intervention

    Device – medical device

    Funding awarded to

    University College London and GOSH

    Planned trial start and expected end date

    March 2022 to January 2027

  • Research area:

    Rare disease

    Disease:

    Fibrodysplasia ossificans progressiva

    Intervention:

    Therapeutics – small molecules

    Phase:

    Phase II

    STOPFOP: Saracatinib Trial TO Prevent FOP

    Intervention

    Therapeutics – small molecules

    Funding awarded to

    University of Oxford

    Public registration details (where available)

    NCT04307953

    Planned trial start and expected end date

    August 2020 to May 2025

  • Research area:

    Rare disease

    Disease:

    Pantothenate kinase associated neurodegeneration

    Intervention:

    Therapeutics – small molecules

    Phase:

    Phase II

    PKAN: Phase II Study of a Novel Vitamin Metabolite (CoA-Z) for Pantothenate Kinase Associated Neurodegeneration

    Intervention

    Therapeutics – small molecules

    Funding awarded to

    University College London Great Ormond’s Street Hospital

    Planned trial start and expected end date

    December 2019 to March 2026

*N/A is used for clinical trials which do not fit into the defined interventional trial phases. For example, those which are assessing the clinical performance of diagnostic devices or observational studies.

Unfortunately, we are not in a position to directly recruit people onto clinical trials. Please ask your doctor or a patient organisation if they know of any clinical trials that you may be eligible to join.

Other ways we can support you

Antibody discovery

Innovative single B-cell technologies and clinically-validated platform to generate fully human therapeutic antibodies.

Diagnostics development

We support all stages of diagnostic development, from assay design through to clinical validation.

Targeted protein degradation

PROTACs and alternative E3 ligases to degrade target proteins that aren’t classically targetable by small molecule inhibitors.

A 3D rendered illustration of proteins

Commercialisation advice

Support your technology transfer to progress your work towards commercially viable products.

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